The Arquer urine take a look at may assist rule out endometrial most cancers

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New research published in the journal BMC Cancer has shown that Arquer Diagnostics’ ADXGYNAE urine test could help improve the diagnostic pathway for women with suspected endometrial cancer.

ADXGYNAE uses patented technology to detect the cancer biomarker Minichromosome Maintenance Complex Component 5 (MCM5).

The study, in which 125 patients participated, showed that ADXGYNAE can accurately detect the presence of an endometrial tumor with a sensitivity of 87.8%. Of these patients, 41 had endometrial cancer, 26 had ovarian cancer, and 58 were benign controls.

Endometrial cancer is the fourth most common cancer in the UK and the sixth most common worldwide, but the diagnostic capabilities are still poor.

Most women who are screened for endometrial cancer will have an invasive uterine lining biopsy. According to Arquet, only 3% to 5% of these procedures lead to a cancer diagnosis.

Richard Edmondson, Professor of Gynecological Oncology at the University of Manchester, the study’s lead researcher, said, “ADXGYNAE is a non-invasive test that has the potential to rule out cancer with high accuracy. We hope that further clinical studies, including a pre-regulatory study in the US, will show that ADXGYNAE, which can be done quickly and easily in NHS hospitals, will reduce the number of women who need these additional procedures to make a diagnosis acknowledge and provide quicker reassurance for those who do not have cancer. “

Arquer Diagnostics has another similar product on the market, ADXBLADDER. ADXBLADDER can rule out the presence of bladder cancer with a negative predictive value of 99% in newly diagnosed patients and patients undergoing routine monitoring.

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